Do you think children today will have a better, worse, or roughly the same life to you?” was a question posed by the Gallup Organisation in 2022 in 64 countries. Globally, only 44% of the adult ...

Worldwide, the incidence of thyroid cancer is increasing, with 586 202 new cases diagnosed in 2020.1 In high-income countries ...

Sub-Saharan Africa has the highest maternal mortality rate in the world, estimated in 2020 to be 545 maternal deaths per 100 000 livebirths, more than 136 times higher than that of the lowest region.1 ...

In an Editorial in July 2023, we wrote with optimism about the antifungal clinical development pipeline. At the time, several ...

Schubert KM, Specht U, Lawn ND, et al. Driving in people with seizures and epilepsy. Lancet Neurol 2025; 24: 486–87—In this Insight, the spelling of author Ulrich Specht's name was incorrect, and the ...

A positive result on the α-synuclein seed amplification assay (SAA) has emerged as the most robust CSF biomarker for the detection of synucleinopathy.1,2 The assay reliably identifies the presence of ...

Severe autoimmune-mediated neuropathies, such as chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) and ...

Blood pressure is frequently elevated in the acute phase of stroke—whether due to cerebral ischaemia or intracerebral ...

Climate change and global warming driven by air pollution and carbon emissions are contributing to worsening respiratory health and increasing numbers of asthma-related emergencies and deaths.

HIV response. Experts are suggesting a projected 24% decrease in HIV funding over the next year in the context of reductions ...

Health registries have become an increasingly powerful tool to document outcomes for particular populations, and are usually grouped around a single disease, procedure, or medication.1 Although health ...

Oesophageal adenocarcinoma has an extremely poor prognosis, and improving outcomes via therapy remains particularly challenging in such a heterogeneous cancer. Another avenue for improving outcomes ...