Khamenei has condemned the attacks and promised to retaliate, saying Israel had "sealed for itself a bitter and painful destiny."

Israeli PM Netanyahu compared Iran's nuclear program to cancer, vowing it must be "cut out." He said Israel will destroy Iran's nuclear, missile, and terror infrastructure, with US support. He also hinted the Iranian regime could collapse under pressure,

As the attacks escalate, with fatalities and injuries reported on both sides, Israel issued the stark warning to Iran.

As tensions rise after Israeli airstrikes on Iran's nuclear sites, Prime Minister Netanyahu accused Iran of plotting against the U.S. president.

Israeli Prime Minister Benjamin Netanyahu spoke with ABC News' Jonathan Karl about Israel's attack on Iran's nuclear program and Iran's retaliation against his country.

RAF jets are being sent to the Middle East, Sir Keir Starmer has announced, after Iran threatened to target UK, French and US bases if the countries help stop strikes on Israel.The prime minister said further military assets are being deployed to provide “contingency support” across the region amid escalating hostilities between the two long-time foes.

The Israeli prime minister then tied Joe Biden in knots over Gaza, and then Lebanon, for the final 15 months of his term. And he has now almost certainly cocked a snook at Donald Trump, who, by most accounts, wanted more time to renegotiate a nuclear deal with Tehran.

As Israeli Prime Minister Benjamin Netanyahu vowed to fight “as long as it takes,” Iran fired missiles at Israel, and Israeli warplanes attacked air defenses around Tehran.