nytimes.com

Most People Don’t Think About Culverts. Their Failure Can Be Deadly.

Scientists simulated what happens when the pipes and tunnels that divert rainwater fail. In one scenario, 30 percent of local residents couldn’t reach an E.R. By Alexander Nazaryan Culverts aren’t ...
FierceBiotech

The future of RAS inhibitors

Revolution Medicines recently made history with the approval of its RAS inhibitor Rasonque for advanced pancreatic cancer. But behind RevMed is an entire field of biotechs working to broaden the reach ...
News Medical

FDA approves first RAS-targeted therapy for metastatic pancreatic cancer

The U.S. Food and Drug Administration (FDA) has approved daraxonrasib, an oral multi-selective RAS(ON) inhibitor, for adults with metastatic pancreatic adenocarcinoma who have received at least one ...
The American Journal of Managed Care

Daraxonrasib Clears FDA as First RAS-Targeted Pancreatic Cancer Drug

The FDA approved daraxonrasib, the first targeted therapy for metastatic pancreatic adenocarcinoma, citing a survival benefit vs chemotherapy. The FDA approved daraxonrasib (Rasonque; Revolution ...
Medscape

FDA Approves RAS Inhibitor Daraxonrasib for Pancreatic Cancer

The FDA has approved the first RAS-targeted therapy for metastatic pancreatic cancer, offering a new treatment option for patients with previously treated disease. Daraxonrasib (Rasonque, Revolution ...
PV Tech

Designing for water: why flood risk must move to the front of utility-scale solar design

Solar projects impact, and are impacted by, watershed conditions extending far beyond the site. Image: Castillo. The risk of flooding to and from solar projects is a growing challenge for the PV ...
www.kingcounty.gov

NE 128th Way Culvert (Fish Passage) Replacement Project

Crews closed NE 128th Way, just west of Avondale Road NE on August 17, 2026, to complete a culvert replacement project. During construction, crews identified additional drainage improvements needed ...
USNI

Navy Removes Head of Drone Programs After 8 Months, PAE Maritime Head Miller Now Leading PAE RAS

Unmanned Surface Vessel Division 12 (Sea Hunter) and 13 (Sea Hunter) conduct unit level training underway in San Diego Bay, California, May 1, 2025. US Navy photo The Navy’s portfolio acquisition ...
Chicago Tribune

Teams build inventory of culverts’ conditions, check to see if fish can go with the flow

Crews hit the road this week to begin creating a database of conditions at culverts, bridges, dams, weirs and other manmade structures in Northwest Indiana streams. Their information will help the ...
VTDigger

Down the tubes: Vermont volunteers crawl culverts to outsmart the next flood

UVM students help clear leaves from a culvert as part of the Culvert Crawlers program. Photo courtesy Charis Boke A tube of corrugated metal running under a road might not look like much. But when the ...
ascopubs.org

Daraxonrasib, a RAS(ON) multi-selective inhibitor vs chemotherapy in previously treated metastatic pancreatic adenocarcinoma (mPDAC): Primary and final analysis from the phase ...

b RAS G12, G13 or Q61 mut or no RAS mut identified. This is an ASCO Meeting Abstract from the 2026 ASCO Annual Meeting II. This abstract does not include a full text component.