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Phase II trial results indicated that treatment with the firm's antisense oligonucleotide led to stable or improved best-corrected visual acuity.
A "productive" meeting with the FDA has given the firm confidence in its regulatory filing and commercialization plans for ST-920.
Patients on Enhertu followed by a chemotherapy and dual anti-HER2 regimen fared better than those on standard therapy.
The team is exploring whether biomarker testing could also identify patients who benefit more from immune checkpoint inhibitors after radiation.
The firm said it is in discussions with the FDA to resubmit its biologics license application seeking approval for Ebvallo.
After establishing dosing and safety in Phase I, researchers will evaluate the drug's anti-tumor activity in patients with PSMA-expressing cancers.
DCx sees potential to build multifunctional ADCs using the same technology Repare used to create its small molecule synthetic lethal therapies.
The firm is studying the combination in the first-line setting for head and neck cancer patients who had a PD-L1 combined positive score of less than 1.
The biotech has nominated MB-111, a drug it's developing as a treatment for elevated triglycerides, as its first clinical development candidate.
Researchers at AACR discussed what's next for the drug class, given the disappointing activity of tiragolumab with Tecentriq ...
Biotech firms are engineering smarter, safer gene delivery systems to enhance the safety and efficacy of genetic medicines.