A division as difficult as the NFC West has become cannot be won in Week 1. But winning or losing the first divisional ...

The SportsLine projection model reveals its picks for the NFL Week 1 game between the San Francisco 49ers and the Seattle ...

Our best bets, picks and predictions for the Seahawks vs. 49ers season opener include a Kenneth Walker prop pick.

The San Francisco 49ers and the Seattle Seahawks open their seasons Sunday. Kickoff from Lumen Field is scheduled for 4:05 ...

USA Today's NFL experts make their picks for a Week 1 showdown between the Seattle Seahawks and San Francisco 49ers ...

San Francisco kicks off 2025 trying to erase the memory of an injury-riddled 2024 campaign, but despite those woes, their ...

The 1,200-yard club for 49ers receivers is an exclusive one. We’re talking Jerry (10 times), T.O. (three times), Dave Parks, ...

The Seattle Seahawks open against the San Francisco 49ers at Lumen Field and are considered underdogs by betting markets.

The 49ers are at the crossroads. They've held onto the same core of players for years, and they're coming off 6-11 season.

The 49ers seek a return to form, the Eagles defend their Super Bowl title and the Chiefs aim to remain atop the AFC.

Here we will look at and discuss some bold predictions for the game between the 49ers and the Seahawks in Week 1 of the 2025 ...

For the 49ers to be competitive again this year, they will not only need quarterback Brock Purdy to return to form, but they ...