Mutations in copper/zinc superoxide dismutase 1 (SOD1), primary causes of human amyotrophic lateral sclerosis (ALS), provoke motor neuron death through an unidentified toxic property. The known ...

Neurons, with their large cell bodies and extensive processes, depend on a delicately balanced intracellular transport machinery to keep in touch with their own outer reaches. Inequalities between ...

The fate of neurons is to be spread thin. Their axons and outlying synapses depend on a constant flow of materials to and from the cell body, making efficient transport a survival skill. Two papers ...

Neurons, specialized cells that transmit information across the nervous system, communicate with each other via projections ...

(Medical Xpress)—Neurons have developed elaborate mechanisms for transporting critical components, like transmitter-laden vesicles, down their axons to the synaptic terminations. An axon in a blue ...

NEW YORK, NY / ACCESSWIRE / October 1, 2021 / David Sans is a noted investor and a philanthropist in the healthcare industry. He looks at how axonal transport can be key to helping people function and ...

A physical dimension of a cell is seldom its Achilles' heel. Yet for the neurons that are affected in most kinds of peripheral neuropathy, it is the length of their axons that best accounts for their ...

Seeking students to contribute to research exploring motor-disease protein complexes and their role in intracellular transport, as they relate to disease initiation and the aging process, and the ...

Alzheimer's dementia is caused by accumulation of amyloid-β protein in neurons, formed from proteolytisis of amyloid precursor protein (APP), but the normal role of APP in the brain remains unclear.