A new technique offers a sharp picture of an elusive and ephemeral stage of a chemical’s life. By precisely measuring the energy of a molecule at the instant it morphs from one form to another, ...

What are the atomic motions at enzymatic catalytic sites on the timescale of chemical change? Combined experimental and computational chemistry approaches take advantage of transition-state analogs to ...

Chemists have devised a technique that allows them to determine the structure of the transition state of a reaction by observing the products that result from the reaction. During a chemical reaction, ...

Hike from one valley to another via a mountain pass, and eventually you'll come to the highest point of your journey, where you'll probably stop briefly to take in the view before descending. That ...