Early stage GIST may be curable, but there is a risk of recurrence. The overall relative 5-year survival rate for GIST is 83 percent, but this varies by stage and other factors. Newer therapies offer ...

Confirming a KIT mutation and assessing disease spread are critical initial steps for GIST management. Understanding the mutational profile helps tailor treatment, as some mutations may resist Gleevec ...

GIST stands for gastrointestinal stromal tumor. When tumors spread from the gastrointestinal (GI) tract to distant tissues or organs, it is called a metastatic GIST. Newer therapies, such as imatinib ...

GISTs begin in special cells that are part of your autonomic nervous system. These cells are located in the wall of the GI tract, and they regulate muscle movement for digestion. The majority of GISTs ...