Forty years ago, a postdoctoral researcher named James McGrath who would go on to spend more than three decades as a clinical geneticist and research scientist at Yale, made a discovery that advanced ...
Parents pass their genes down to their kids, with a child inheriting about 50% of their genome from each parent. But there is another kind of genetic code known as the epigenome that can also be ...
Traditionally, differences among individuals have been divided into genetic and environmental causes. However, both types of variation can underlie regulatory changes in gene expression — that is, ...
The question of how the effects of genetic variants combine to produce continuous traits, such as height and blood pressure, as well as complex diseases, including diabetes and Alzheimer’s disease, ...
The COVID-19 pandemic gave us tremendous perspective on how wildly symptoms and outcomes can vary between patients experiencing the same infection. How can two people infected by the same pathogen ...
Scientists have long known that the DNA code in genes is not the only way to pass genetic traits from parents to offspring. "Epigenetic" marks—chemical modifications to DNA that don't change the DNA ...
Genetic information in the DNA and modifications, such as DNA methylation, define the epigenetic landscape and phenotype and show both Mendelian and non-Mendelian heredity. Scientists have long known ...
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