Deep-learning algorithms enhance mutation detection in cancer and RNA sequencing

Researchers from the Faculty of Engineering at The University of Hong Kong (HKU) have developed two innovative deep-learning ...
Seeking Alpha

Nature Methods Paper Leverages PacBio Sequencing Technology to Develop the Platinum Pedigree Benchmark, a New Standard for Accurate Characterization of Variation in the Human ...

MENLO PARK, Calif., Aug. 04, 2025 (GLOBE NEWSWIRE) -- PacBio (PACB), a leading provider of high-quality, highly accurate sequencing platforms, today announced the results of a study published in ...
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PacBio Celebrates Nature Methods Naming Long-Read Sequencing "Method of the Year"

MENLO PARK, Calif., Jan. 13, 2023 /PRNewswire/ -- PacBio (NASDAQ: PACB), a leading developer of high-quality, highly accurate sequencing solutions, today celebrated long-read sequencing being named ...
BioTechniques

Long-read sequencing expedites rare disease diagnoses

Long-read sequencing is being harnessed to improve the rate of rare disease diagnosis. Researchers at the University of California Santa Cruz (CA, USA) have demonstrated that long-read sequencing (LRS ...
The Scientist

Revving the Motor: Full-Length Protein Sequencing with Nanopore Technology

Protein sequencing presents different challenges than nucleic acid sequencing, meaning that proteomics has yet to benefit as much as genomics from the next-generation sequencing revolution. However, ...
Labroots

Techniques and Tips: Learn Sample Preparation for Next Generation Sequencing

Next Generation Sequencing (NGS) provides comprehensive genomic information about disease, development, and other biological processes. Though the NGS workflow has been vastly simplified, there are ...
GEN

Long-Read Nanopore Sequencing Improves Rare Disease Diagnosis

Whole genome sequencing (WGS) is not necessarily a solution for someone with a rare, monogenic disease. Indeed, more than half of families with suspected rare monogenic diseases do not have an answer ...
Nanowerk

Paving the way for solid-state, label-free DNA sequencing technologies

Nanopore sensors are tiny devices used to detect and analyze individual molecules by measuring ionic changes as the molecules pass through nanometer-scale openings. These sensors are classified into ...
news.ucsc

New AI tool detects hidden cancer mutations

Every cancer carries a unique genetic fingerprint: variations in DNA known as “somatic variants” that occur in tumor DNA but are absent from the patient’s healthy cells. While some cancers may also ...
BioTechniques

Low-cost whole-genome sequencing monitors cancer from blood tests

A combined whole-genome sequencing approach could be used to detect and monitor cancer from liquid biopsies. It is challenging to monitor cancer from liquid biopsies due to the low concentrations of ...