Researchers at the University of California San Diego have developed a large-scale screening approach that identifies ...

After nearly four decades of research, Mayo Clinic scientists have revealed the molecular structures of protein kinase C beta ...

A first-in-class nanoparticle injection sneaks antibodies into pancreatic cancer cells to clear mutant KRAS, shrinking tumors ...

The concepts of ‘gene’ and ‘protein’ have evolved markedly since their original use. Early geneticists, beginning with Gregor Mendel in the 1800s, described invisible hereditary ‘factors’, and it was ...

After nearly four decades of research, Mayo Clinic scientists have revealed the molecular structure of protein kinase C beta (PKCβ), a key protein linked to cancer and neurological diseases. The ...

Protein-protein interactions (PPIs) are fundamental to operating cellular processes, as they regulate and coordinate various biological activities within the cell. These interactions govern a wide ...

Cellular membrane proteins play important roles in cellular transport, signaling, and cell-to-cell communication. Malfunction in membrane proteins can lead to serious diseases, such as cancer. However ...

By combining CRISPR knock-in with small peptide tags, researchers can study proteins in their native cellular context, ...

Targeted protein degradation (TPD) has moved from promising concept to near-commercial reality in under a decade. By hijacking the cell’s ubiquitin-proteasome system, TPD therapies eliminate ...

International nanoscientists publish a new blueprint reframing the protein corona as a programmable navigation interface to cross the blood-brain barrier.