Persistent depressive disorder, known as dysthymia or low-grade depression, is less severe than major depression but more chronic. It occurs twice as often in women as in men. Persistent depressive ...

Researchers have identified a brain mechanism that may determine why chronic pain leads to depression in some individuals but not others. The findings suggest the brain initially adapts to persistent ...

What’s it called when you feel sad or hopeless for weeks, months, or even years? If you’re thinking depression, yes, that’s true. But it could also be persistent depressive disorder (PDD), also known ...

Depression is among the most widespread mental health disorders worldwide, affecting an estimated 1 in 20 people. It is ...

Chronic pain has long been known to be associated with depression. Among adults with chronic pain, around 40% exhibit clinical symptoms of depression. But why is it that only some people with chronic ...

In a recent study published in the BMC Medicine, a group of researchers identified the factors influencing the variability in depression prevalence among chronic pain sufferers and developed clinical ...

Depression affects everyone differently, and finding the right treatment can take time. Learn how to recognize when it might ...

Older adults with chronic disease who have less education, lower income, and no active jobs tend to experience symptoms of depression.

A new study investigating neuroinflammation in the ventral tegmental area (VTA) of the brain, a small, midbrain dopaminergic region, has found that acute and chronic depression are associated with ...

Black youth and adults in the U.S. are more likely than white adults to experience persistent symptoms of depression, but are less likely to seek help from a mental health professional, according to ...

Four in ten adults with chronic pain experience clinically significant depression and anxiety, reported a new systematic review and meta-analysis published in JAMA Network Open. "Right now, we have ...