A team of researchers at VCU Massey Comprehensive Cancer Center has identified a new pathway through which mutations in the tumor suppressor p53 gene—found very frequently in human tumors—hijack DNA ...
Pharmacogenomic trial of CPT-11-docetaxel in untreated patients (P) with advanced non small cell lung cancer (NSCLC). A phase II study of the Spanish Lung Cancer Group (SLCG). Correlation with the ...
The tumor suppressor protein p53 plays a critical role in preventing cancer by regulating cell cycle, apoptosis, and genomic stability. However, mutations in the P53 gene are found in over 50% of ...
The p53 gene plays an important role in cell biology as it regulates the cell cycle and halts the formation of tumors. While the gene was discovered more than four decades ago, researchers are still ...
Investigation of the association of CTRB2 exon 6 deletion with time to progression and overall survival in pancreatic ductal adenocarcinoma. This is an ASCO Meeting Abstract from the 2025 ASCO ...
Researchers have elucidated the role of the p53 gene in ulcerative colitis. The study suggests a potential new drug target to stop disease progression to cancer. Researchers in the lab of Michael ...
Chemotherapy kills cancer cells. But the way these cells die appears to be different than previously understood. Researchers have now uncovered a completely new way in which cancer cells die: due to ...