A new study published in PLOS Genetics has identified an extreme mutational hotspot within the genome of Pseudomonas fluorescens, providing unprecedented insight into the relationship between gene ...

The William H. Foege Genome Sciences Building at the University of Washington School of Medicine in Seattle contains laboratories, sequencers, computational facilities, and other resources for ...

Mutation rate, as a biological process, denotes the frequency at which heritable changes in nucleotide sequence arise per genome, gene, or nucleotide per cell division or per unit time, driven by ...

Using sequencing instruments from multiple vendors, scientists from the University of Utah Health, the University of Washington, PacBio, and elsewhere have developed what they claim is the most ...

Scientists have discovered a key 'survival gene' that prevents strains of tuberculosis (TB) from mutating into drug-resistant 'superbugs'. In a joint study, published today, Friday January 27th 2017, ...

Retrospective study of fluoropyrimidine chemotherapy dosing and toxicity in patients with screen-detected deleterious DPYD gene variants. Real-world treatment patterns, healthcare resource utilization ...

Researchers from Karolinska Institutet have discovered how mammalian cells prevent the gradual buildup of harmful mutations in mitochondrial DNA, the small but vital genome that powers every cell. The ...

Several mutations in a single gene can cause the rare and hard-to-diagnose syndrome, known as catacholamineric polymorphic ventricular tachycardia (CPVT). CPVT strikes children during physical ...