A research team led by Professor Dae-ha Seo at the Department of Physics and Chemistry, Daegu Gyeongbuk Institute of Science and Technology, has successfully developed a new technology for optical ...

Membrane fluidity is a crucial parameter for cellular physiology. Recent evidence suggests that fluidity varies between cell types and states and in diseases. As membrane fluidity has gradually become ...

In biology, seeing can lead to understanding, and researchers in Professor Edward Boyden's lab at the McGovern Institute for Brain Research are committed to bringing life into sharper focus. With a ...

Expansion microscopy (ExM) 1 physically magnifies preserved biological specimens by covalently anchoring biomolecules and/or their labels to a swellable polymer network (such as sodium polyacrylate) ...

Our remarkable ability to perform complex tasks—such as thinking, observing, and touch—stems from proteins, the tiny nanometer-sized molecules in the body. Despite decades of research, our ...

Cell membranes play a crucial role in maintaining the integrity and functionality of cells. However, the mechanisms by which they perform these roles are not yet fully understood. Scientists from the ...

Collaboration between researchers at the University of Geneva, Institut de biologie structurale de Grenoble, and the University of Fribourg has shown how lipids and proteins in cell membranes react in ...

Cryogenic optical microscopy uncovers multiple conformations of PIEZO1 in cell membranes, offering atomic-scale insights into how cells sense force. The team focused on PIEZO1, a mechanosensitive ion ...

Escherichia coli bacteria imaged by high-speed inline force mapping and fluorescence microscopy. Simultaneous topography and elastic modulus maps show a stiffening of the division site. Light and ...

A pandemic-era breakthrough has allowed scientists to literally expand our view of plankton. By using ultrastructure expansion microscopy, researchers visualized the inner workings of hundreds of ...

Current optical and electron microscopy imaging techniques are not suited for measuring the dynamic characteristics of living microorganisms at tiny scales due to complex sample preparation methods or ...

Fluorescent image of PIEZO1 in native cell membrane (left) and an artistic representation of its conformational states resolved with Ångström precision (right). Our remarkable ability to perform ...