Sometimes cancer cells are able to cross into the fluid that surrounds and protects your brain and spinal cord. Cancer drugs you take by mouth or through a vein can’t get through as easily.

Please provide your email address to receive an email when new articles are posted on . Early intrathecal therapy effectively resolved symptoms related to high-grade neurotoxicity among patients who ...

Intrathecal baclofen (ITB) therapy has evolved into a standard treatment for severe spasticity. After this therapy had been provided for 10 years, a retrospective chart review on 50 patients, ...

PHILADELPHIA (WPVI) -- Pain is one of the most common problems for cancer patients. They often struggle to find relief or with side effects from the powerful narcotics often used for pain. There's an ...

A novel indwelling subcutaneous intrathecal catheter circumvented the complex spine anatomy of patients with spinal muscular atrophy (SMA), a challenge when giving nusinersen via intrathecal injection ...

Practitioners from around the country who have extensive experience in intrathecal baclofen (ITB) therapy gathered in early 2004 to develop best-practice guidelines for ITB therapy. Discussion focused ...

Objectives: To evaluate the efficacy of intrathecal baclofen (ITB) for upper extremity spastic hypertonia in tetraplegia of spinal origin. Setting: University of Alabama at Birmingham hospital.

Intrathecal drug administration via lumbar puncture and a spinal access port device led to serious complications in a patient receiving experimental therapy for Niemann-Pick type C. In a case report ...

Phase II multicentric Italian trial on repositioning of the antipsychotic drug chlorpromazine and its combination with temozolomide in patients with MGMT unmethylated glioblastoma: The RACTAC trial.

Reports of pump failure, dosing errors, as well as other possible safety issues have prompted the Agency to issue the alert to make prescribers aware of the dangers associated with using medications ...