A component of the human interferon system that activates SARS-CoV-2 cellular defenses appears to be defective in a proportion of humans, new research reports. COVID-19 outcomes were more severe in ...

The innate immune system fights infectious agents, and the alarm messenger interferon plays a central role in this. However, if interferon is produced in the absence of an infection, it can lead to ...

When pathogens attack the body, the innate immune system goes to work protecting against the invading disease. The innate immune system is the first line of defense. It detects precisely what the ...

In a new study, researchers from Johns Hopkins Medicine say they have uncovered insights as to why lupus symptoms and severity present differently in individuals with the autoimmune condition, which ...

The paper E.N. Judd et al., “Positive natural selection in primate genes of the type I interferon response,” BMC Ecol Evol, 21:65, 2021. In humans, one of the host cell’s first lines of defense ...

These intercellular messages, ferried about by molecules called interferons, serve as a warning signal to nearby cells—“‘You are about to be infected; it’s time for you to set up an antiviral state,’” ...

Interferon receptor knockout chickens uncover how type I and III interferons differentially shape avian antiviral immunity and influenza disease outcomes.

DALLAS – Nov. 16, 2001– Researchers at UT Southwestern Medical Center at Dallas and the Baylor Institute for Immunology Research in Dallas have linked abnormal secretion of alpha interferon to the ...

The immune system uses a special mechanism to protect children from novel viruses—and it typically saves them from a severe course of COVID-19 in two different ways. In the mucous membranes of their ...

Question: I have been prescribed a drug called Intron A for chronic hepatitis C and I don't understand how it works. My physician tells me I can't go without it, but until I learn how it works, I ...