The complement system, a central arm of innate immunity, comprises a network of plasma and membrane-bound proteins that detect and eliminate pathogens. In severe COVID-19, SARS-CoV-2 triggers ...
Researchers at the Francis Crick Institute, King's College London and Complutense University of Madrid have shown that γδ T ...
Prognostic significance of undetectable baseline HPV circulating tumor DNA in oropharyngeal cancer. The ELIMINATE trial: A phase II/III randomized trial evaluating omission of radiotherapy to regional ...
Toll-like receptor 3 (TLR3) is a pattern recognition receptor mainly known for its role in innate immune response to infection. Indeed, binding of double-stranded RNA (dsRNA) to TLR3 triggers a ...
When thinking about the immune system, most people think about B and T cells and how they can be trained to recognize pathogens, preventing re-infections. Besides this "adaptive" immune system, we ...
Unlike transient innate immune activation, trained immunity is characterized by long-lasting but reversible functional reprogramming of monocytes, macrophages, natural killer (NK) cells, and ...
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