The most comprehensive map of the developing human thymus sheds light on how immune responses are built and maintained at early life, with implications for understanding and treating immunodeficiency, ...

CD8 + cytotoxic T lymphocytes (CTLs) serve as central effectors in cancer immunotherapy by directly eliminating tumor cells. However, current clinical therapies face significant limitations. These ...

An initiative partly funded by the Wellcome Trust Sanger Institute in the UK has moved further towards its goal of producing a 'human cell atlas' (HCA) to map every cell type in the human body.

The immune system acts as a critical sentinel of organismal aging, integrating the sensing of physiological states with the execution of defense and clearance functions. Immunosenescence not only ...

Immune cells like T cells watch for invaders in the body. (Artur Plawgo/iStock/Getty Images Plus) In the army of defenders ...

Every individual’s immune system is distinct and changes over time, affecting their health and disease response. Recently, researchers mapped human immune cells to explore what defines a healthy ...

Human peadiatric thymus image from the IBEX protein multiplex (44 proteins on the same image) platform. Thymic epithelial cells are labeled with DEC205 (cyan), pan-cytokeratin (purple), keratin 5 (red ...