Opioid antagonism with naltrexone alters neural responses to threatening stimuli and reduces subjective distress, supporting ...

The mid-1980s was the era of cocaine and marijuana, when “Just Say No” was the centerpiece of the war on drugs and the government’s efforts to stem drug use and addiction. Since then, prescription ...

The overdose-reversing drug naloxone has been rightly hailed as a lifesaving breakthrough, saving countless lives from opioid ...

Placebo effects, in which patients experience relief without therapeutic treatment, increasingly have been considered as potentially powerful clinical treatments for ailments such as depression and ...

Fear and anxiety help defend us against harm, and are largely controlled via neural circuits of interconnected nerve cells and synaptic activity in the brain's amygdala that allow neurons to pass ...

Globally, opioid overdose deaths are more common than you think. It is one of the most important public health concerns, ...

The opioid epidemic is devastating America. Overdoses have passed car crashes and gun violence to become the leading cause of death for Americans under 55. The epidemic has killed more people than HIV ...

The search for a safer opioid has followed pain medicine for decades. Doctors still need strong drugs for surgery, major ...

Studies show that ibogaine can be effective for short-term opioid addiction treatment, especially reducing drug cravings and some withdrawal symptoms.