DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone cross-links (DHCs) occur frequently within ...
This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...
A Northwestern Medicine study has revealed a previously unknown connection between two fundamental cellular processes, ...
A cell protein previously believed only to provide a scaffolding for DNA has also been shown to directly influence DNA transcription into RNA – the first step of the process by which an organism's ...
In a recent study published in the journal Science Advances, a group of researchers investigated the role of histone modifications in human aging by developing and evaluating histone-specific age ...
Researchers used Google DeepMind’s AlphaFold2 and ProteinMPNN to speed development of antibody-based probes that can be used to see key functions and chemical changes inside living cells as they ...
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