GIST originates in stromal tissue, differentiating it from epithelial-based GI cancers, and is classified as a sarcoma. Symptoms include fullness, fatigue, and GI bleeding, necessitating awareness and ...
GISTs originate from interstitial cells of Cajal and are staged by size, location, mitotic rate, and genetic mutations, influencing treatment strategies. Diagnosis involves imaging, endoscopy, biopsy, ...
Vanek’s tumour, also called an inflammatory fibroid polyp (IFP), is a rare, non-cancerous growth from the submucosa of the gastrointestinal tract. We report the case of a woman in her mid-50s who came ...
Less than 5% of GI stromal tumors (GISTs) are driven by the loss of the succinate dehydrogenase (SDH) complex, resulting in a pervasive DNA hypermethylation pattern that leads to unique clinical ...
These study authors hope their findings will inform future research on gastrointestinal stromal tumors (GIST) and close care gaps for minority patient populations. Unfavorable trends in the diagnosis ...
Prognostic analysis of gastrointestinal stromal tumor by mitotic activity, size of tumor and mutational type of C-Kit protein No significant financial relationships to disclose. This is an ASCO ...
The tumor microenvironment (TME) is a complex and dynamic network consisting of tumor cells, immune cells, stromal cells, extracellular matrix (ECM), cytokines, and growth factors, all interacting to ...
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