Complete mucosal healing is a key therapeutic goal in inflammatory bowel disease (IBD). While ferroptosis-mediated epithelial cell death is known to compromise the mucosal barrier as the cornerstone ...
Crypt-base-columnar cells are continuously dividing intestinal stem cells that generate IECs, which are composed by distinct specialised cell types that play different functions: Enterocytes (in the ...
Even when we hear that a gene related to Crohn's disease has been discovered, it is not immediately clear in which intestinal ...
Northwestern Medicine scientists have discovered a previously unknown process used by epithelial cells to alleviate epithelial tissue crowding and avoid cell damage and loss, according to a recent ...
Epithelial cells line the body’s surfaces to protect against physical damage, pathogens, and dehydration. These cells play key roles in absorbing nutrients and removing waste products, as well as ...
The epithelium, a layer of cells that forms a protective barrier between the body and the outside world, was the first ...
In vitro modeling of small airway epithelium for studying barrier function and mucociliary clearance
The small airways serve as a primary line of defense against inhaled particles and facilitate gas exchange by directing air to the alveoli. These small airways are critical in the pathophysiology of ...
Scientists discovered a population of cells that can start the process of programmed cell death, survive it, and then help rapidly rebuild damaged tissue. Their descendants become far more resistant ...
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