"Training" of precursors of white blood cells leads to a sustained positive response of the hematopoietic system. This effect could help accelerate the formation of new white blood cells, which are ...

Research reveals that T cells from the adaptive immune system can manipulate the memory of innate immune cells. Previously, it was believed that the memory of innate immune cells operated ...

The innate immune system plays a crucial role in regulating host-microbe interactions, and especially in providing protection against pathogens that invade the mucosa. Using an intestinal infection ...

The first peer-reviewed journal in the field of human gene therapy, providing all-inclusive coverage of the research, methods, and clinical developments that are driving today's explosion of gene ...

The human immune system is split into the innate immune system and the adaptive immune system. Both systems work in harmony to protect us from infections and disease. Here, we discuss their ...

Detecting pathogen invasion and regulating homeostatic processes are two essential functions of myriad non–Toll-like innate immune proteins. One of the more important revolutions in immunology has ...

STING, RIG-I and NLRP3 agonists might increase the effectiveness of immuno-oncology checkpoint inhibitors, while antagonists of these targets offer an anti-inflammatory bonus. Drug developers have ...