An analysis of somatic mutations in blood exomes from 200,618 individuals revealed previously unrecognized genes driving clonal hematopoiesis. Mutations in these genes showed age-dependent clonal ...

Clonal hematopoiesis of indeterminate potential (CHIP) is an age-related condition associated with increased mortality among patients with cancer. CHIP mutations with high variant-allele frequencies ...

$${T}_{i\to i-1}=\frac{\left(n-i\right)}{\left(1+s\right)i+\left(n-i\right)}\times \frac{i}{n}$$ $${T}_{i\to i+1}=\frac{\left(1+s\right)i}{\left(1+s\right)i+\left(n-i ...

In a recent study published in the journal Nature Genetics, a team of researchers from the United Kingdom (U.K.) and the United States (U.S.) analyzed whole blood samples from a large cohort of U.K.