Early low-dose lenalidomide significantly reduces mutational burden without increasing AML risk in non-transfusion-dependent del(5q) MDS.
Clonal hematopoiesis of indeterminate potential (CHIP) is an age-related condition associated with increased mortality among patients with cancer. CHIP mutations with high variant-allele frequencies ...
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Sleep and exercise can tame the mutant blood cells that quietly drive heart disease
Mutant blood cells that accumulate silently in bone marrow as people age can sharply raise the risk of coronary heart disease ...
A comprehensive new study from deCODE genetics published in Nature Genetics, provides insights into the epidemiology and somatic and germline genetics of clonal hematopoiesis. Whole genome sequence ...
A new editorial paper titled "Exploring clonal hematopoiesis and its impact on aging, cancer, and patient care" has been published in Aging. In this new editorial, researchers Julieta Elena Rodriguez, ...
Results from METIS (EF-25), an international, multicenter phase III randomized study evaluating the efficacy and safety of tumor treating fields (TTFields) therapy in NSCLC patients with brain ...
New insights reveal how hidden genetic mutations could be silently fueling heart disease in middle-aged adults, paving the way for personalized prevention strategies. In a recent study published in ...
In a recent study published in the journal Nature Genetics, a team of researchers from the United Kingdom (U.K.) and the United States (U.S.) analyzed whole blood samples from a large cohort of U.K.
The blood system changes over time: a subset of stem cells outcompete their neighbors and gradually take over blood production. In addition, the blood stem cell reservoir shrinks and becomes dominated ...
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