A new review reveals how the unfolded protein response, a cellular stress-signalling network, helps tumours evade immune ...

Discover how regular exercise supercharges your immune system at a cellular level. Learn how physical activity mobilizes ...

A new review in the Journal of Translational Medicine proposes that the physical mechanics of solid tumors govern whether ...

A researcher at the Hackensack Meridian Center for Discovery and Innovation (CDI) and physician-scientist colleagues from Hackensack Meridian Health have shown how a critical pathway is fundamental to ...

A recent review highlights amino acid sensors as central regulators linking nutrient availability to tumor adaptation. By coordinating metabolic homeostasis, epigenetic remodeling, antitumor immunity, ...

Immune checkpoint inhibitors are cancer therapeutics that have shown remarkable success in extending lives in many cancers, including melanoma, MSI-high cancers, and other cancers. However, these ...

The maternal immune system must tolerate a semiallogeneic foetus while preserving defence against pathogens. Regulatory T cells (Tregs), marked by expression of FOXP3 and CD25, accumulate in the ...

How do bacteria adapt when resources run low? ISTA researchers have found that, under starvation stress, E. coli can use ...

How do bacteria adapt when resources run low? ISTA researchers have found that, under starvation stress, E. coli can use bacteriophages and CRISPR-Cas ...