Dysfunctions of the tiny cell processes (primary cilia) of the pancreatic beta cells could be a cause of type 2 diabetes. Little is known about the structure and function of these cilia. An ...
The nuclear pore complex (NPC) is a eukaryotic cellular structure that regulates bidirectional traffic of macromolecules across the nuclear envelope. Solving the intricate structure of this ~120-MDa ...
Tight junctions (TJs) regulate paracellular permeability, cell polarity and cell mechanics of barrier-forming tissues. This Review explores how TJs adapt their structure and function across tissues, ...