Alternative splicing, a clever way a cell generates many different variations of messenger RNAs—single-stranded RNAs involved in protein synthesis—and proteins from the same stretch of DNA, plays an ...

A multi-institutional group of researchers led by Children's Hospital of Philadelphia (CHOP) has linked a strong cancer driver gene to changes in proteins that regulate alternative splicing. The ...

Removal of introns from messenger RNA precursors (pre-mRNA splicing) is an essential step for the expression of most eukaryotic genes. Alternative splicing enables the regulated generation of multiple ...

Alternative mRNA splicing is an important mechanism for regulating gene expression and generating transcriptomic diversity. Most cases of alternative splicing studied to date are triplet, meaning that ...

Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism ...

Alternative splicing, a clever way a cell generates many different variations of messenger RNAs - single-stranded RNAs involved in protein synthesis - and proteins from the same stretch of DNA, plays ...

A recent study highlights the pivotal role of alternative splicing in controlling plant secondary metabolism, which is crucial for producing bioactive compounds with significant medicinal and ...

What eventually becomes a graduate student’s PhD thesis work is rarely the project they initially pursued. However, in rare cases like with recent PhD graduate Dr. April Lo from Dr. Alice Berger’s Lab ...

Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism ...

In a new study, researchers demonstrate that deregulation of a protein called RBFOX2, involved in RNA splicing, contributes to the progression and metastasis of pancreatic cancer. Pancreatic cancer ...

A study in zebrafish shows that neuronal microexons regulate brain activity by modulating cAMP signaling. Loss of these ...

A multi-institutional group of researchers has linked a strong cancer driver gene to changes in proteins that regulate alternative splicing. The researchers created new computational tools and ...