A Rule of Chemistry Stood for 100 Years. Now, Scientists Have Broken It—Twice.

Researchers synthesized weird molecules that exist in three dimensions, breaking Bredt's rule and helping to develop future ...
Science Daily

Scientists just overturned a 100-year-old rule of chemistry, and the results are “impossible”

Chemists at UCLA are showing that some of organic chemistry’s most famous “rules” aren’t as unbreakable as once thought. By ...
The Debrief

Defying Longstanding Chemical Rules, Chemists Have Engineered Exotic Molecules They Say Could “Benefit Our World”

UCLA researchers have violated Bredt’s rule, a century-old principle of organic chemistry, challenging our understanding of molecular shapes.

A year after undermining Bredt's rule, scientists make cage-shaped, double-bonded molecules that defy expectations

Organic chemistry is packed with rules about structure and reactivity, especially when it comes to making and breaking ...
C&EN

2 unusual alkenes stretch the limits of molecular geometry

Cubene and quadricyclene are descended from cubane and quadricylane, both cage-shaped structures with bonds that are fairly ...
Nature

The scope and mechanism of palladium-catalysed Markovnikov alkoxycarbonylation of alkenes

Figure 1: Challenges and application potentials for the palladium-catalysed Markovnikov alkoxycarbonylation of alkenes. In addition to ethene, propene and butene are the most important industrial ...