Understand the stages of a standard RNA-seq bioinformatics workflow, including the role of QC, alignment, gene expression quantification, and specialized application analyses Identify key QC metrics ...

In a recent study published in the journal Nature Methods, a group of researchers developed a novel method called Ribonucleic Acid (RNA) High-Order Folding Prediction Plus (RhoFold+). This deep ...

Essentially all cells in an organism's body have the same genetic blueprint, or genome, but the set of genes that are actively expressed at any given time in a cell determines what type of cell it ...

Researchers from A*STAR Genome Institute of Singapore (A*STAR GIS) have developed a new method to study individual RNA molecules and reveal how their structures influence gene regulation, a ...

When RNA molecules are synthesized by cells — a critical process in the creation of proteins and other cellular functions — they typically undergo a series of “folding” events that determine their ...

The answer depends on the questions you’re trying to answer, as well as the origin, quantity, and quality of your samples. In this article, we’ll briefly discuss several RNA-seq workflows, how they ...

SINGAPORE – Researchers from A*STAR Genome Institute of Singapore (A*STAR GIS) have developed a new method, called ‘sm-PORE-cupine’, to study individual RNA molecules and reveal how their structures ...

A team of researchers at IOCB Prague led by Prof. Michal Hocek has developed a novel method for preparing ribonucleic acid (RNA) containing modified bases. Innovative use of engineered DNA polymerases ...