SARS-CoV-2, the virus responsible for COVID-19, infects cells by binding its spike protein to angiotensin-converting enzyme 2 (ACE2) receptors. Blocking this interaction with inhibitors could prevent ...

Study reveals how the JAK inhibitor lowers ACE2 expression and viral entry in individuals with a genetic risk variant linked to autoimmune diseases. Study: Tofacitinib Mitigates the Increased SARS-CoV ...

Researchers at Demokritus University of Thrace, Institute of Applied Biosciences Centre for Research and Technology Hellas, National Hellenic Research Foundation and University of Athens have ...

Patients infected by the COVID-19 virus may benefit from treatments that dampen the renin–angiotensin system, according to a review of several animal studies. These preclinical findings generally ...