The arrival of Crew-10 paves the way for the return of NASA astronauts Williams and Wilmore and their Crew-9 mates Nick Hague (NASA) and Aleksandr Gorbunov (Roscosmos). Williams's and Wilmore's return was delayed due to problems faced by Boeing 's Starliner spacecraft that brought them to ISS in the first place.

SpaceX's Crew-10 mission has successfully launched from NASA's Kennedy Space Center in Florida at 7:03PM Eastern on March 14. NASA astronauts Anne McClain and Nichole Ayers, Japan Aerospace Exploration Agency's Takuya Onishi and Roscosmos cosmonaut Kirill Peskov are onboard and will join the ISS crew after the spacecraft docks with the orbiting lab at 11:30PM Eastern time on March 15.